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FDA Grants Approval for First Skin Cancer Drug

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The U.S. Food and Drug Administration approved the first drug to treat basal cell carcinoma, the most common form of skin cancer, on Monday.

Erivedge (vismodegib), marketed by San Francisco-based Genentech, won expedited FDA approval under a priority review program for drugs that may represent a major treatment advance. In a statement, the agency said the once-daily pill treats basal cell skin cancer that has metastasized, or spread, and is designed for cases deemed unsuitable for surgery or radiation.

Basal cell carcinoma, which is usually a slow-growing and painless form of cancer, starts in the top layer of skin and is typically caused by frequent exposure to sunlight and other forms of ultraviolet radiation. Estimates say one in five Americans will develop it in their lifetime — but caught early, it’s highly treatable.

Researchers evaluated the safety and effectiveness of Erivedge in a clinical study of 96 people with locally advanced or metastatic cancer. In the latter group, 30 percent had at least a partial response to the drug, while 43 percent of people with locally advanced basal cell had at least a partial response.

Side effects of Erivedge included muscle spasms, hair loss, weight loss, nausea, diarrhea, fatigue, distorted sense of taste, decreased appetite, constipation and vomiting. Because of the potential risk for death or severe birth defects to a fetus, the drug will be packaged with a label warning and won’t be prescribed to pregnant women.

Texas Tech v Texas
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Longhorns’ Spelling Error Delights Rival Fans

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In the University of Texas' media guide, it didn't take long at Big 12 Media Days to discover that "Texas" was misspelled.  

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Category: East Texas News Tags: ,
police-lights
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Accident Victim Was A Teen On Her Way To Freshman Orientation at SFA

 

A bad accident Wednesday night claimed the life of an Austin woman, and Stephen F Austin said she was on her way to freshman orientation.

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Category: East Texas News, News Tags: , ,
Win McNamee, Getty Images
Win McNamee, Getty Images
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Governor Perry Is Sending Troops To The Texas-Mexico Border

Governor Rick Perry announced Monday he was sending a thousand troops to the border with Mexico to combat the border crisis, and said that process will happen over the next month.

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Malaysian Airlines Flight Reported Missing On Route To Beijing
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Malaysian Passenger Jet With 295 Onboard Crashes Near Ukraine-Russia Border [UPDATED]

A Malaysia Airlines jet carrying nearly 300 people crashed near the border between Russia and Ukraine, according to Reuters and Interfax. The airline company has confirmed that it has lost contact with the plane, a Boeing 777.

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Stuart Scott
ESPN, YouTube
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Watch Stuart Scott’s Heartbreaking Speech at the ESPYs [VIDEO]

Longtime ESPN personality Stuart Scott literally took center stage at Tuesday night's ESPY Awards when he accepted the Jimmy V Perseverance Award. And his speech did not disappoint.

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Category: News, Sports, Television Tags:
McAllen Police Dept
McAllen Police Dept
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Texas Judge Arrested for DWI

Late Saturday night, Nora Longoria, a justice with the 13th Court of Appeals in McAllen was arrested and charged with suspicion of DWI. 

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Category: Texas News Tags:
Christopher Furlong/Getty Images
Christopher Furlong/Getty Images
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Thousands Help Lone Survivor After Her Family Is Killed in Spring, TX

After her family was killed execution style last Wednesday near Houston, people are coming out in droves to help the 15-year old sole survivor.

Cassidy Stay's parents and four siblings were killed in the shootings at their home, but Cassidy survived after a bullet grazed her head and she played dead until the violence ended. Now almost $300,000 has been raised for her benefit, as she starts her new life without her family.

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Getty Images-Online USA
Getty Images-Online USA
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Lone Ranger Outfit Brings In Big Bucks at Texas Auction

The family of a late businessman and collector decided to put the original Lone Ranger outfit on the auction block, and it brought in $195,000 at the auction in Waco Saturday.

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Monkey Business
Monkey Business
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Three Weeks Left To Nominate a Lufkin Small Business Of The Year

Do you have a favorite ice cream shop, burger joint, lawn service or barber?  Tell everyone about them!

Now is the time to nominate your favorite Mom or Pop shop for Small Business of the Year with the Lufkin Chamber of Commerce.

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Category: East Texas News, News Tags: ,
David McNew/Getty Images
David McNew/Getty Images
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Game Wardens Have Been Targeting Lakes Looking for Drunk Boaters

If one of your favorite things to do during the summer is pack some frosty beverages on ice and head to the lake, be safe when you hop on the boat!

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Category: East Texas News, News Tags:

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